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Long-term ipsilateral recurrence and contralateral risk following surgery for primary spontaneous pneumothorax in
Daichi Ishii1,2, Nozomi Hatanaka3, Miho Aoyagi1
1Department of Thoracic Surgery, Sapporo City General Hospital, Sapporo, Japan.
Insights
Younger patients (≤19 years) with primary spontaneous pneumothorax (PSP) have higher recurrence rates after surgery. Prolonged follow-up, at least 3 years, is recommended for this age group to monitor for recurrence and new pneumothorax events.
Area of Science:
- Thoracic surgery
- Pulmonology
- Pediatric surgery
Background:
- Primary spontaneous pneumothorax (PSP) is prevalent in young individuals.
- Optimal follow-up duration and age-specific recurrence risks post-surgery for PSP are not well-defined.
Purpose of the Study:
- To evaluate long-term surgical outcomes for PSP in patients aged ≤19 years compared to those aged 20-29 years.
- To assess recurrence rates and postoperative imaging findings based on age groups.
Main Methods:
- Retrospective analysis of 357 patients (aged 10-29 years) who underwent thoracoscopic bullectomy with pleural covering.
- Patients were categorized into ≤19 years (further divided into ≤15 and 16-19 years) and 20-29 years age groups.
- Comparison of clinical data, recurrence rates, and CT findings; recurrence-free survival analyzed using Kaplan-Meier method.
Main Results:
- Patients aged ≤19 years exhibited higher crude rates of ipsilateral recurrence (12.3%) and contralateral pneumothorax (18.1%) compared to the 20-29 year group.
- The ≤15-year subgroup showed the highest crude recurrence rates.
- Postoperative CT scans revealed new bullae in both age groups, with contralateral events observed even after 5 years.
Conclusions:
- Younger PSP patients, especially those ≤15 years, demonstrate a higher tendency for postoperative recurrence and contralateral pneumothorax.
- Age-specific follow-up strategies for a minimum of 3 years are recommended despite non-significant differences in recurrence-free survival on Kaplan-Meier analysis.
Background:
Primary spontaneous pneumothorax (PSP) is common in young individuals, but age-specific recurrence risks and optimal follow-up durations remain unclear. Therefore, we aimed to evaluate the long-term outcomes of PSP surgery, including recurrence and imaging findings, in patients aged ≤19 years and those aged 20-29 years.
Methods:
We retrospectively analyzed data concerning 357 patients (aged 10-29 years) who underwent thoracoscopic bullectomy with pleural covering between 2012 and 2021. Patients were grouped into two categories: patients aged ≤19 years (subdivided into those aged ≤15 and 16-19 years) and those aged 20-29 years. Clinical data, recurrence rates, and postoperative computed tomography (CT) findings were compared between the groups. Recurrence-free survival was analyzed using the Kaplan-Meier method and a log-rank test.
Results:
Patients aged ≤19 years showed higher crude rates of ipsilateral recurrence (12.3% vs. 3.9%, P=0.005) and contralateral pneumothorax (18.1% vs. 4.6%, P<0.001) than those aged 20-29 years, with the highest crude recurrence observed in the ≤15-year subgroup. However, recurrence-free survival did not differ significantly among age groups on Kaplan-Meier analysis. Most recurrences occurred within 2 years, but contralateral events were observed beyond 5 years. Postoperative CT revealed new bullae [at least one at the apex, segment 6 (S6), or staple line] in both groups.
Conclusions:
Younger patients with PSP, particularly those aged ≤15 years, showed a clinically relevant tendency toward higher postoperative recurrence and contralateral pneumothorax, warranting careful and prolonged follow-up. Although time-to-event analyses did not demonstrate statistically significant age-related differences in recurrence-free survival, age-specific follow-up strategies for a minimum of 3 years are recommended.
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