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Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
Published on: September 18, 2013
Long-Term Outcomes in Tyrosine Hydroxylase Deficiency: A Case Series of Four Paediatric Patients
Rong Ren1, Aiyun Yuan1, Mei Hou1
1Qingdao Women and Children's Hospital, Qingdao University, Shandong, China.
Abstract:
This study aims to investigate the clinical characteristics and long-term outcomes of patients with TH gene-related dopa-responsive dystonia (DRD), which providing further insights into this disorder. In this study, we analysed the clinical data, genetic test results and 3-year follow-up information of four patients treated with levodopa. Detailed clinical information was collected on these patients, and the results of genetic testing were analysed. Among the four patients, there were two males and two females with the age of onset ranging from 5 months to 2 years. At the same time, we review relevant literature about the clinical spectrum, treatment and prognosis.
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