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Related Concept Videos

Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

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Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
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Related Experiment Video

Updated: Apr 17, 2026

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
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A modified David V: Technique and outcomes from a large single centre experience.

Robert Fleck1, Melissa G Medina1, Christopher K Mehta1

  • 1Division of Cardiac Surgery, Northwestern University Feinberg School of Medicine Bluhm Cardiovascular Institute, Chicago, IL 60611, USA.

Asian Cardiovascular & Thoracic Annals
|April 16, 2026
PubMed
Summary

This study shows that a modified David V valve-sparing aortic root replacement technique offers excellent survival and freedom from reoperation rates. Meticulous surgical technique and careful valve assessment are key to successful outcomes in aortic root surgery.

Keywords:
Aortic aneurysmDavid VDavid procedureStanford modificationaortic surgeryreimplantation techniquevalve sparing aortic root replacement

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Area of Science:

  • Cardiovascular Surgery
  • Thoracic Surgery
  • Aortic Surgery

Background:

  • Composite valve-graft replacement is standard for aortic root replacement.
  • Valve-sparing aortic root replacement (VSARR) preserves the native aortic valve.
  • Refinements in VSARR techniques, including remodeling and reimplantation, have improved outcomes.

Purpose of the Study:

  • To describe the technical steps and outcomes of a modified David V procedure for VSARR.
  • To evaluate the early and midterm results of this adapted Stanford modification.

Main Methods:

  • Retrospective review of 185 patients who underwent adapted Stanford modification VSARR between November 2007 and March 2025.
  • Data collected from a prospectively maintained institutional database.
  • Analysis of patient demographics, procedural details, and clinical outcomes.

Main Results:

  • Mean patient age was 47.6 years, with 81% males.
  • Low mortality (0.5%) and no 30-day reinterventions.
  • Excellent midterm results with 1, 5, and 10-year survival rates of 99%, 98%, and 92%, respectively.
  • High freedom from aortic valve or re-operation rates: 99% (1 year), 97% (5 years), and 94% (10 years).
  • No cases of greater than moderate aortic insufficiency on early echocardiographic follow-up.

Conclusions:

  • Meticulous surgical technique and thorough valve assessment are crucial in VSARR.
  • The modified David V procedure demonstrates favorable early and midterm outcomes.
  • Graft type and size appear less critical than surgical precision in VSARR.