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Related Concept Videos

Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

484
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
484
Mitral Regurgitation III: Medical Management01:25

Mitral Regurgitation III: Medical Management

617
Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
617
Mitral Valve Prolapse II: Assessment and Management01:22

Mitral Valve Prolapse II: Assessment and Management

1.3K
IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
1.3K
Mitral Valve Prolapse I: Introduction01:27

Mitral Valve Prolapse I: Introduction

1.0K
IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
1.0K
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

1.2K
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
1.2K
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

1.6K
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
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Related Experiment Video

Updated: Apr 17, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
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5-Year Follow-Up After Transcatheter Mitral Valve Replacement Using the Cardiovalve System.

Rimantas Benetis1, Matteo Saccocci2, Egle Rumbinaite3

  • 1Department of Cardiac, Thoracic and Vascular Surgery, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.

JACC. Case Reports
|April 16, 2026
PubMed
Summary
This summary is machine-generated.

Transcatheter mitral valve replacement (TMVR) with the Cardiovalve device shows excellent 5-year durability and safety in high-risk patients with severe mitral regurgitation (MR). This approach offers sustained clinical and hemodynamic benefits, addressing limitations of surgical repair.

Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Medical Devices

Background:

Keywords:
TMVRmitral regurgitationmitral valvemitral valve replacementtranscatheter procedure

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  • Severe mitral regurgitation (MR) poses treatment challenges, especially in high-risk patients unsuitable for surgery.
  • Existing transcatheter mitral valve replacement (TMVR) options have limited long-term durability data.
  • Anatomical constraints can limit the efficacy of edge-to-edge mitral valve repair techniques.