Related Experiment Video
Updated: Apr 17, 2026

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
Disparities in Finding Delirium in Critically Ill Latinos
Ana Lucia Fuentes1, Charlotte C Ellberg2, Humberto Parada3
1Division of Pulmonary, Critical Care and Sleep Medicine, University of California, San Diego, CA.
Objectives:
Delirium is common in the ICU and is associated with devastating consequences. However, the accuracy of delirium detection tools has not been evaluated when patient-provider language discordance is present. This study aimed to assess the accuracy of delirium screening practices in Spanish-speaking ICU patients, evaluate whether caregiver-administered tools improve detection amid language barriers, and examine language-based differences in delirium care.
Design:
Prospective observational cohort study.
Setting:
Two MICUs at the University of California, San Diego.
Patients:
142 ICU patients and 100 caregivers were enrolled between August 2024 and January 2025.
Interventions:
Usual-Care (Confusion Assessment Method [CAM]-ICU completed by bedside providers), Reference-standard (English or Spanish-language CAM-ICU performed by research staff), and FAM-CAM (English or Spanish-language Family-CAM administered by caregivers).
Measurements And Main Results:
Among 71 English-speakers, 34 female (47%), with a mean ( sd ) age of 62 years (16). Among 71 Spanish-speakers, 26 female (37%) and the mean age was 60 years (15). The prevalence of delirium was 39% overall, affecting 26 (37%) English-speakers and 32 (45%) Spanish-speakers. Agreement between Usual-Care and Reference-standard was higher in English-speakers than in Spanish-speakers (κ=0.71 vs. κ=0.11; z=-4.98, p < 0.01), with 72% of delirium missed in Spanish-speakers. Among Spanish-speakers, FAM-CAM showed higher agreement with Reference-standard than did Usual-Care (κ=0.68 vs. κ=0.11; z= -4.69, p < 0.05) and reduced the rate of missed delirium by 47%. Spanish-speakers were more deeply sedated (mean Richmond Agitation Sedation Scale -1.46 [ sd 1.38] vs. -0.77 [ sd 1.31]; mean difference 0.69; 95% CI, 0.24 to 1.14, p < 0.01) and had higher odds of restraint use (odds ratio 4.53; 95% CI 1.91 to 10.74; p < 0.01) than English-speakers.
Conclusions:
Usual-Care demonstrated poor accuracy in delirium detection among Spanish-speakers, who also experienced deeper sedation and more frequent restraint use than English-speakers. FAM-CAM improved delirium detection among Spanish-speakers and may help overcome language barriers to equitable delirium detection.
Related Concept Videos
Stereotypes, Prejudice, and Discrimination
Bias in Epidemiological Studies
Drug Dosing: Geriatric Patients
Barriers to Effective Communication II
Cultural barriers:
Differences in values, beliefs, religion, knowledge, and tradition can significantly impact communication. Awareness of nonverbal cues is critical, especially when conversing with a patient from a different culture. What appears appropriate in one culture may be inappropriate in another.
Semantic barriers:
As a result of their tendency to use...
Positive Symptoms Schizophrenia: Hallucinations and Delusions
Hallucinations
Hallucinations in...
Documentation of Nursing Diagnosis
In some settings, data-driven computerized decision support systems are in place, allowing for more accurate nursing diagnoses. The database within one of these systems includes diagnostic labels defining characteristics, activities, and indicators for nursing. A nurse enters...

