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Updated: Apr 18, 2026

A Modified Two Kidney One Clip Mouse Model of Renin Regulation in Renal Artery Stenosis
Published on: October 26, 2020
Renal Artery Stenosis Detected Early Through Routine Health Checkups
Shinji Kishimoto1, Tatsuya Maruhashi1, Masato Kajikawa2
1Division of Radiation Medical Science, Department of Regenerative Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
Background:
Routine health checkups may contribute to the early detection of renal artery stenosis and enable timely intervention before irreversible renal damage occurs in patients with renovascular hypertension.
Case Summary:
A 66-year-old man undergoing an annual health checkup was found to have progressive renal dysfunction over 1 year with increasing home blood pressure. Imaging revealed severe (90%) left renal artery stenosis without renal atrophy. Preserved renal size and cortical structure, low intrarenal resistive index, and minimal albuminuria indicated retained renal viability. Percutaneous transluminal renal angioplasty with stent implantation resulted in blood pressure reduction and stabilization of renal function at the 6-month follow-up.
Discussion:
This case demonstrates the value of combining routine health checkups with viability-based assessments to guide revascularization.
Take-Home Message:
Early detection of renal artery stenosis through routine health checkups and renal viability assessment may enable effective revascularization in selected patients.
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