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Related Concept Videos

Acute Coronary Syndrome I: Introduction01:30

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Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
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Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

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The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
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Related Experiment Video

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Author Spotlight: Enhancing Coronary Artery Revascularization
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Isolated First Septal Perforator Spontaneous Coronary Artery Dissection Causing Acute Myocardial Infarction.

Ryan A Karlsson1, John Birrane1, Rory O'Hanlon2

  • 1Department of Cardiology, St James's Hospital, Dublin, Ireland.

JACC. Case Reports
|April 16, 2026
PubMed
Summary

This case study highlights a rare instance of spontaneous coronary artery dissection (SCAD) in the first septal perforator artery (S1) in a young male. Cardiac MRI confirmed a significant septal infarction, emphasizing SCAD as a cause of chest pain.

Area of Science:

  • Cardiology
  • Vascular Medicine
  • Diagnostic Imaging

Background:

  • Spontaneous Coronary Artery Dissection (SCAD) of the first septal perforator (S1) is an uncommon condition.
  • Previous reports primarily involve female patients.
Keywords:
cardiac magnetic resonancefirst septal perforatorliterature reviewspontaneous coronary artery dissection

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