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Protective Effects of Ozone against Quinolinic Acid-Induced Redox Imbalance in Murine BV-2 Microglial Cells

Pedro Henrique Zatti1, Nicole Peyrot da Silva1, Marina Rigotti1

  • 1Laboratory of Oxidative Stress and Antioxidants, Biotechnology Institute, University of Caxias do Sul, Caxias do Sul, RS, Brazil.

Neurotoxicity Research
|April 16, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Kynurenine pathwayNeurodegenerationNeurogliaOzone therapy

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In the presence of oxidizing agents, phenols are oxidized to quinones. Quinones can be easily reduced back to phenols using mild reducing agents. The electron-donating hydroxyl group enhances the reactivity of the aromatic ring, enabling oxidation of the ring even in the absence of an α hydrogen.
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