Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Formation of the Platelet Plug

Formation of the Platelet Plug

The platelet phase, the second stage of hemostasis, commences around 15-20 seconds after an injury. It follows and overlaps with the vascular phase, during which blood vessels constrict to minimize blood loss.
As the injured blood vessel contracts, endothelial cells undergo contraction, revealing collagen fibers in the basement membrane and underlying connective tissue. Furthermore, the plasma membrane of endothelial cells becomes adhesive, preparing the site for platelet adhesion. Platelets...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Radiographic Sacroiliitis Progression in Psoriatic Arthritis.

Rheumatology (Oxford, England)·2026

Same author

Do Patients Diagnosed with Psoriatic Arthritis Before or Concurrently with Psoriasis Have Different Disease Phenotype and Outcomes?

The Journal of rheumatology·2026

Same author

Understanding the transition from psoriasis to psoriatic arthritis: the role of targeted therapy.

EULAR rheumatology open·2026

Same author

Body mass index and achievement of minimal disease activity in psoriatic arthritis across different classes of advanced therapy.

Rheumatology (Oxford, England)·2026

Same author

Variable Selection for Illness-Death Processes Under Dual Observation Schemes.

Statistics in medicine·2026

Same author

Two-phase designs for biomarker studies when disease processes are under intermittent observation.

Biometrics·2026

Same journal

Minor histocompatibility antigen TCR-T.

Blood advances·2026

Same journal

Increased Gene Therapy Efficacy Through the Use of Extended Half-Life Clotting Factors.

Blood advances·2026

Same journal

Bone Mineral Density in Hemophilia and VWD.

Blood advances·2026

Same journal

Differential perforin sensitivity drives lineage-dependent resistance to CAR T-cell killing in blood cancer cell lines.

Blood advances·2026

Same journal

Pediatric autoimmune hemolytic anemia is associated with a high incidence of underlying immune disorders.

Blood advances·2026

Same journal

Predictive Modeling of Clonal Hematopoiesis Across Diverse Cohorts.

Blood advances·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Apr 18, 2026

Microfluidics in Assessing Platelet Function

Microfluidics in Assessing Platelet Function

Published on: November 8, 2024

Vein-to-vein data: what predicts platelet response?

Nicole Relke^1,2,3, Richard J Cook⁴, Donald M Arnold¹

¹Michael G. DeGroote Centre for Transfusion Research, Department of Medicine, McMaster University, Hamilton, ON, Canada.

|April 16, 2026

Summary

No abstract available in PubMed .

More Related Videos

Microfluidic Flow Chambers Using Reconstituted Blood to Model Hemostasis and Platelet Transfusion In Vitro

Microfluidic Flow Chambers Using Reconstituted Blood to Model Hemostasis and Platelet Transfusion In Vitro

Published on: March 19, 2016

Investigating von Willebrand Factor Pathophysiology Using a Flow Chamber Model of von Willebrand Factor-platelet String Formation

Investigating von Willebrand Factor Pathophysiology Using a Flow Chamber Model of von Willebrand Factor-platelet String Formation

Published on: August 14, 2017

Related Experiment Videos

Last Updated: Apr 18, 2026

Microfluidics in Assessing Platelet Function

Microfluidics in Assessing Platelet Function

Published on: November 8, 2024

Microfluidic Flow Chambers Using Reconstituted Blood to Model Hemostasis and Platelet Transfusion In Vitro

Microfluidic Flow Chambers Using Reconstituted Blood to Model Hemostasis and Platelet Transfusion In Vitro

Published on: March 19, 2016

Investigating von Willebrand Factor Pathophysiology Using a Flow Chamber Model of von Willebrand Factor-platelet String Formation

Investigating von Willebrand Factor Pathophysiology Using a Flow Chamber Model of von Willebrand Factor-platelet String Formation

Published on: August 14, 2017