Cardiovascular-Related Maternal Mortality

Area of Science:

• Cardiology
• Maternal Health
• Public Health

Background:

• Cardiovascular disease (CVD) is the primary cause of pregnancy-related mortality in the U.S.
• Black women experience disproportionately high rates of CVD-related maternal deaths.
• Key risk factors include hypertension, diabetes, dyslipidemia, and obesity.

Purpose of the Study:

• To review major contributors to cardiovascular-related maternal deaths.
• To emphasize the importance of preconception and postpartum care for cardiovascular risk management.
• To discuss evidence-based approaches for managing CVD in reproductive-aged women.

Main Methods:

• Review of evidence-based approaches for cardiovascular risk management in reproductive-aged women.
• Discussion of preconception counseling and risk assessment tools (e.g., modified WHO 2.0 classification).
• Analysis of diagnostic tools (e.g., NT-proBNP testing) for differentiating cardiac symptoms from pregnancy-related conditions.

Main Results:

• Prepregnancy optimization of risk factors mitigates cardiovascular risk during pregnancy.
• Validated tools and specific testing aid in accurate CVD assessment and diagnosis.
• Evidence-based management strategies exist for conditions like cardiomyopathy, myocardial infarction, and hypertensive disorders of pregnancy.

Conclusions:

• Standardized perinatal CVD risk assessment algorithms are essential.
• Postpartum remote monitoring programs can help address disparities.
• Integrated preconception and postpartum care are vital for reducing maternal CVD mortality.