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Multi-dimensional terahertz detection for methamphetamine using microporous metal Metasurfaces and multi-wavelength

Mingxin Li1, Yu Zhou2, Zixubo Li1

  • 1College of Criminal Science and Technology, Jilin Police College, Changchun 130117, China.

Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
|April 16, 2026
PubMed
Summary
This summary is machine-generated.

This study introduces a novel terahertz (THz) time-domain spectroscopy (THz-TDS) method for enhanced methamphetamine detection. Combining microporous metal metasurfaces with multi-wavelength optical pumping significantly improves sensitivity and detection limits.

Keywords:
MethamphetamineMicroporous metal metasurfaceMulti-wavelength optical pumpingTHz time-domain spectroscopy

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Area of Science:

  • Optoelectronics
  • Spectroscopy
  • Materials Science

Background:

  • Terahertz (THz) detection methods often lack sensitivity and information dimensionality.
  • Methamphetamine detection requires highly sensitive and specific analytical techniques.

Purpose of the Study:

  • To develop an enhanced THz time-domain spectroscopy (THz-TDS) detection method for methamphetamine.
  • To improve the sensitivity and information dimension of THz detection using microporous metal metasurfaces and multi-wavelength optical pumping.

Main Methods:

  • Fabrication of a microporous aluminum metasurface using laser processing.
  • Coating methamphetamine standard solution on the metasurface.
  • Irradiation with 405 nm, 450 nm, and 780 nm lasers, individually and combined.
  • Measurement of THz absorption spectra, refractive indices, and dielectric constants.

Main Results:

  • Local field enhancement by the metasurface significantly improved THz wave-sample interaction.
  • Multi-wavelength laser pumping modulated THz response by influencing molecular energy levels and carrier concentration.
  • The method achieved a linear response for methamphetamine detection (10 μg/mL–100 μg/mL) with R² > 0.997.
  • A limit of detection (LOD) of 10 μg/mL was achieved, five orders of magnitude lower than conventional methods.

Conclusions:

  • The "metasurface enhancement + multi-wavelength optical pumping" scheme provides a robust theoretical and experimental basis for rapid methamphetamine detection.
  • Laser wavelength and metasurface's local surface plasmon resonance (LSPR) effect synergistically enhance THz detection capabilities.
  • This approach offers a significant advancement in sensitive and selective chemical detection.