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Updated: Apr 18, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
The duality of estrogen
Skylar Cassity1, Elizabeth Gould1
1Princeton Neuroscience Institute, Princeton University, Princeton, NJ 08540, USA.
Abstract:
Estrogen enhances cognition under healthy and pathological conditions. In this issue of Neuron, Hokenson et al.1 describe findings that counter this view, demonstrating that high levels of brain estrogen during acute intense stress impair memory. This preview discusses their findings in context of stress-induced pathology and resilience.
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