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Related Experiment Video

Updated: Apr 18, 2026

Inducing Long-Term Plasticity of Intrinsic Neuronal Excitability in Neurons of the Dorsal Lateral Geniculate Nucleus

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Published on: September 20, 2024

Binding as an enabling mechanism for cross-modal plasticity.

Woon Ju Park¹, Tansu Celikel²

¹School of Psychology, Georgia Institute of Technology, Atlanta, GA, USA.

Neuroscience and Biobehavioral Reviews

|April 16, 2026

Summary

Early blindness triggers cross-modal plasticity, where the brain reorganizes sensory processing. This adaptation uses a binding mechanism, linking co-occurring signals to maintain function while processing new sensory information.

Keywords:

Binding Blindness Cortical reorganization Cross-modal plasticity Functional specialization Hebbian learning

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Cross-Modal Multivariate Pattern Analysis

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Cross-Modal Multivariate Pattern Analysis

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Published on: November 9, 2011

Area of Science:

Neuroscience
Sensory processing
Brain plasticity

Background:

Early-onset blindness leads to the visual cortex processing non-visual information, a phenomenon termed cross-modal plasticity.
The underlying mechanisms of this sensory reorganization remain incompletely understood.

Purpose of the Study:

To propose a unifying framework for cross-modal plasticity based on the general learning mechanism of binding.
To explain how the visual cortex adapts to auditory or tactile inputs while preserving its original functional roles.

Main Methods:

The study proposes a theoretical framework based on Hebbian plasticity and competitive selection.
It integrates concepts of intrinsic circuitry and top-down modulation to explain adaptive reorganization.

Main Results:

The proposed binding mechanism explains how deprived visual cortices adapt computations to new sensory statistics.
This framework reconciles functional constancy (e.g., motion analysis) with computational flexibility in cross-modal processing.

Conclusions:

Cross-modal plasticity is framed as a feature extraction process driven by binding, linking co-occurring sensory signals.
This perspective offers mechanistic insights for rehabilitation strategies following sensory loss across different life stages.