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CLO26-081: Extracellular Vesicle-Derived Tissue Factor as a Biomarker for Cancer-Associated Thrombosis: A Systematic

Ujjwal Soni1, Prachi Dawer2, Akshit Chitkara3

  • 11University of Oklahoma Health Campus, Oklahoma City, OK.

Journal of the National Comprehensive Cancer Network : JNCCN
|April 16, 2026
PubMed
Abstract

No abstract available in PubMed .

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Integrins act both as extracellular input receivers and as intracellular processing activators. As their name suggests, integrins are entirely integrated into the membrane structure. Their hydrophobic membrane-spanning regions interact with the phospholipid bilayer's hydrophobic region. These membrane receptors provide extracellular attachment sites for effectors like hormones and growth factors. They activate intracellular response cascades when their effectors are bound and active.
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