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Application of melanin and its engineered nanomaterials in tumor radiotherapy: a review

Cheng Chen1, Yong Guo2,3

  • 1Department of Oncology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.

Journal of Translational Medicine
|April 17, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Bidirectional roleMelaninNanomaterialsRadioprotectionRadiotherapyRadiotherapy sensitization

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.