Related Experiment Video
Updated: Apr 18, 2026

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
Published on: January 25, 2016
Prospective Short-Term Observation for Spontaneous Recovery of Sudden Sensorineural Hearing Loss
Seoyun Jang1, Han-Seul Na1, Seokhwan Lee1
1Department of Otorhinolaryngology-Head and Neck Surgery and Biomedical Research Institute, Pusan National University Hospital, Busan.
Objective:
To determine the rate of spontaneous recovery in sudden sensorineural hearing loss (SSNHL) within 1 week of onset and evaluate the effect of corticosteroid treatment in patients without early recovery.
Study Design:
Prospective, non-randomized comparative study.
Setting:
Tertiary academic medical center.
Patients:
Patients with SSNHL who presented within 3 days of onset between September 2023 and December 2024.
Intervention:
Patients were observed for 1 week from the onset, followed by corticosteroid therapy only in insufficient early recovery group.
Main Outcome Measures:
Pure-tone average (PTA), word recognition score (WRS), and hearing gain.
Results:
Among 41 patients who completed the 3-month follow-up, 13 (31.7%) showed complete or partial recovery after 1 week and were classified into the observation group. The remaining 28 patients (68.3%) received corticosteroid therapy. At the end of the observation, the observation group showed significantly better PTA (17.7±8.0 dB), WRS (94.2±3.5%), and hearing gain (36.4±12.3 dB) than the treatment group ( P <0.001). Frequency-specific analysis demonstrated significant spontaneous recovery across all measured frequencies (250 to 8000 Hz, P <0.05). Logistic regression identified initial PTA as the only significant predictor of spontaneous recovery, with a cutoff value of 71 dB (AUC=0.934). In the treatment group, PTA improved significantly from the end of observation to 3 months (mean change: 33.8±23.9 dB, P <0.001).
Conclusions:
Approximately one-third of patients with SSNHL recovered spontaneously within 1 week. Initial PTA was the strongest predictor of spontaneous recovery, with a threshold of 71 dB. For patients with limited early recovery, corticosteroid therapy resulted in meaningful hearing improvement.
Related Concept Videos
Neurogenesis and Regeneration of Nervous Tissue
Unrenewable Cells
Photoreceptors
The retina is composed of several layers and contains specialized cells called photoreceptors. The photoreceptors (rods and cones) change their membrane potential when stimulated by light energy. There are two types of photoreceptors—rods and cones—which differ in the shape of...
Secondary Spinal Cord Injury llI: Pathophysiology
Auditory Pathway
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking...

