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Distal nerve transfers for radial nerve reinnervation and hand function restoration
Andrija Savić1,2, Jovan Grujić1,2, Aleksandar Djurdjević3,4
1Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
Brain & Spine
|April 17, 2026
Summary
Distal median-to-radial nerve transfers effectively restore hand extension in patients with radial nerve palsy. This procedure significantly improves wrist, finger, and thumb function, enhancing overall quality of life.
Area of Science:
- Neurosurgery
- Orthopedics
- Reconstructive Surgery
Background:
- Radial nerve palsy causes significant functional deficits, including wrist drop and loss of hand extension.
- Direct nerve repair or grafting may be insufficient for extensive radial nerve injuries.
Purpose of the Study:
- To evaluate the efficacy of distal median-to-radial nerve transfers in restoring hand extension.
- To assess the impact of this nerve transfer on patients' quality of life.
Main Methods:
- A prospective study involving nine patients with radial nerve injuries.
- Surgical technique included transferring median nerve branches to the radial nerve and posterior interosseous nerve.
- Pronator teres to extensor carpi radialis brevis tendon transfer was used for chronic cases.
- Functional recovery and quality of life were assessed using standardized scales (BMRC, PNSQoL).
Main Results:
- All patients demonstrated satisfactory recovery of wrist, finger, and thumb extension (BMRC M3-M5).
- Predominant outcomes were M4-M5, particularly for wrist extension.
- Patient-reported quality of life significantly improved, with 88.9% reporting excellent outcomes.
Conclusions:
- Distal median-to-radial nerve transfer is a reliable method for restoring hand extension in proximal radial nerve injuries.
- The procedure leads to significant improvements in patient-reported outcomes and quality of life.
- Larger multicenter studies are recommended to further validate these findings.
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