Determinants for Congenital Clubfoot in Ethiopia: A Case-Control Study at Black Lion Specialized Hospital

Seid Mohammed Abdu1, Birhanu Ayana2, Girma Seyoum3

  • 1Department of Medical Anatomy, School of Biomedical Science, College of Medicine and Health Sciences Wollo University Dessie Amhara Region Ethiopia.

Health Science Reports
|April 17, 2026
PubMed

Insights

Congenital clubfoot in Ethiopia is linked to low education, male gender, family history, smoking, chronic illness, and alcohol use. Awareness and support for pregnant women are crucial for prevention and management.

Area of Science:

  • Pediatrics
  • Public Health
  • Genetics

Background:

  • Clubfoot is a common congenital deformity, disproportionately affecting children in low- and middle-income countries.
  • Ethiopia lacks observational studies on factors influencing clubfoot, despite its public health significance.
  • Congenital clubfoot remains an overlooked concern, particularly in children under five.

Purpose of the Study:

  • To investigate the determinants of congenital clubfoot in Ethiopian children.
  • To identify risk factors associated with clubfoot deformity.

Main Methods:

  • An institution-based, unmatched case-control study was conducted at Black Lion Specialized Hospital.
  • 284 participants (96 cases, 188 controls) were enrolled.
  • Data were analyzed using SPSS 25, employing frequency, percentage, and logistic regression.

Main Results:

  • Significant factors associated with clubfoot include lack of formal education (AOR=8.29), chronic illness (AOR=2.57), smoking exposure (AOR=4.83), alcohol history (AOR=5.39), male gender (AOR=2.08), and family history of clubfoot (AOR=12.78).

Conclusions:

  • Key determinants identified: low education, male gender, family history, smoking, chronic illnesses, and alcohol use.
  • Findings highlight the need for increased awareness among pregnant women regarding potential determinants.
  • Empowering pregnant women with knowledge and providing nutritional support can aid in managing congenital clubfoot.
Abstract

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