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An explainable multi-head attention network for healthcare IoT threat detection based on the MedDefender-MHAN
1Department of Information Systems and Cybersecurity, College of Computing and Information Technology, University of Bisha, Bisha, Saudi Arabia.
Plos One
|April 17, 2026
Summary
MedDefender-MHAN offers an explainable intrusion detection system for Internet of Medical Things (IoMT) security. It achieves high accuracy and real-time explanations, ensuring regulatory compliance for healthcare IoT.
Area of Science:
- Cybersecurity
- Artificial Intelligence in Healthcare
- Internet of Medical Things (IoMT)
Background:
- Healthcare environments face critical cybersecurity risks due to the proliferation of Internet of Medical Things (IoMT) devices.
- Existing deep learning intrusion detection systems (IDS) lack the explainability required for clinical adoption and regulatory compliance (e.g., GDPR, FDA).
Purpose of the Study:
- To present MedDefender-MHAN, an explainable multi-head attention network for healthcare IoT threat detection.
- To embed interpretability directly into the network architecture for real-time explanations, unlike post-hoc methods.
Main Methods:
- A novel dual-stream architecture combining Convolutional Neural Networks (CNNs) and Transformer-based encoders.
- Integration of interpretability within the multi-head attention mechanism for gradient-weighted explanation generation.
- Evaluation on CICIDS2017 and TON_IoT benchmark datasets.
Main Results:
- Achieved high detection accuracies of 99.47% (CICIDS2017) and 98.92% (TON_IoT).
- Demonstrated sub-3ms inference latency and a throughput of 435 samples per second.
- Explainability evaluation showed 94.6% alignment with expert signatures and 91.9% temporal accuracy, outperforming post-hoc methods.
Conclusions:
- MedDefender-MHAN provides a clinically viable and regulatory-compliant security solution for healthcare IoMT infrastructure.
- The framework addresses the need for trustworthy AI-driven security with methodological transparency and clinical impact.
- It offers a practical approach to enhancing cybersecurity in regulated healthcare settings.