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Updated: Apr 19, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
Paradigm Shift in Nonhormonal Treatment Options for Vasomotor Symptoms of Menopause
Abstract:
Menopause is a natural physiologic process that typically occurs during the midlife years. Menopause may present with a variety of symptoms, with up to 80% of people reporting vasomotor symptoms (VMS). Although hormonal therapy is the most effective for bothersome VMS, some individuals cannot take hormones due to a contraindication or may prefer alternative methods. With only three U.S. Food and Drug Administration-approved nonhormonal treatment options for bothersome VMS of menopause, the newer options of neurokinin receptor antagonists may offer additional benefits with improved sleep and quality of life. Nurses play a critical role in being up-to-date with treatments for bothersome menopausal symptoms to provide care that optimizes the health span.
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