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Hepatic IFRD1 suppresses metabolic dysfunction-associated fatty liver disease via GLUD1/α-KG axis

Mengya Geng1, Fanzheng Meng2, Hairui Li2

  • 1Department of Endocrinology and Metabolism, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China; School of Clinical Medicine, Wannan Medical College, Wuhu 241002, China; Anhui Provincial Key Laboratory of Metabolic Health and Panvascular Diseases, Hefei 230001, China.

Science Bulletin
|April 17, 2026
PubMed

Keywords:
Glutamate dehydrogenase 1H3K36me3Interferon-related developmental regulator 1Mitochondria

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