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Related Experiment Videos

H2 breath tests during diarrhea.

N W Solomons, R García, R Schneider

    Acta Paediatrica Scandinavica
    |March 1, 1979
    PubMed
    Summary
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    The hydrogen breath test is not reliable for measuring carbohydrate malabsorption in children with active diarrhea. Results were significantly lower in children experiencing diarrhea compared to healthy controls.

    Area of Science:

    • Pediatric Gastroenterology
    • Diagnostic Technologies

    Background:

    • Carbohydrate malabsorption is a common issue in pediatric gastrointestinal disorders.
    • Hydrogen breath tests are a noninvasive method to assess carbohydrate digestion and absorption.

    Purpose of the Study:

    • To evaluate the reliability of the hydrogen breath test for diagnosing carbohydrate malabsorption in children with active gastroenteritis and diarrhea.

    Main Methods:

    • Administered a 10g dose of lactulose to children.
    • Measured peak breath hydrogen and excess pulmonary hydrogen excretion.
    • Compared results between children with active diarrhea and healthy controls.

    Main Results:

    • Children with active gastroenteritis and diarrhea showed significantly lower peak breath hydrogen and excess pulmonary hydrogen excretion compared to controls.

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  • The hydrogen breath test results were diminished during active diarrheal episodes.

    • Conclusions:

    • The hydrogen breath test is not recommended for assessing carbohydrate malabsorption during active diarrhea in children.
    • Gastroenteritis and diarrhea interfere with the accuracy of hydrogen breath test results.