Design of MOSAAIC (Multi-Ethnic Observational Study in American Asian and Pacific Islander Communities)

Area of Science:

• Epidemiology
• Public Health
• Health Disparities

Background:

• Asian American (AsA) and Native Hawaiian and Pacific Islander (NHPI) populations are significantly underrepresented in U.S. health research.
• This underrepresentation limits understanding of their unique health burdens and disparities.

Purpose of the Study:

• The MOSAAIC (Multi-ethnic Observational Study in American Asian and Pacific Islander Communities) cohort study aims to enhance the understanding of cardiovascular disease and other health conditions prevalent in AsA and NHPI groups.
• It seeks to identify and address health disparities affecting these communities.

Main Methods:

• MOSAAIC will enroll 11,500 adults aged 18+ across five U.S. regions with tailored outreach and broad eligibility criteria.
• The study includes in-person examinations measuring clinical, functional, and anthropometric data, alongside multilingual surveys on health influences.
• Long-term follow-up will track major health events like myocardial infarction, stroke, heart failure, and mortality.

Main Results:

• N/A

Conclusions:

• MOSAAIC is established by the National Institutes of Health as a vital resource for extensive epidemiologic research.
• The study focuses on factors influencing cardiometabolic, pulmonary, and mental health within diverse AsA and NHPI populations.