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Non-invasive Assessment of Microvascular and Endothelial Function
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Expanded field swept-source OCT angiography biomarkers associated with microvascular complications of diabetes

Matthew J Finn1,2, Edward S Lu1,2, Xinyi Ding1,2

  • 1Harvard Retinal Imaging Lab, Boston, MA, USA.

Graefe'S Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie
|April 18, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Diabetes mellitusDiabetic kidney diseaseDiabetic peripheral neuropathyOptical coherence tomography angiography

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Diabetic Retinopathy01:27

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DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
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Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
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