Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cellulose and Pectic Polysaccharides01:15

Cellulose and Pectic Polysaccharides

5.5K
 Every plant cell has a cell wall that protects the cell, provides structural support, and gives the cell shape. Cellulose, the main structural component of the plant cell wall, makes up over 30% of plant matter. It is the most abundant organic compound on earth.  Cellulose is an unbranched polysaccharide composed of linear chains of glucose molecules linked by β (1→4) glycosidic bonds.
As a cell matures, its cell wall specializes according to its type. For example, the...
5.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

LRRC4 functions as a neuron-protective role in experimental autoimmune encephalomyelitis.

Molecular medicine (Cambridge, Mass.)·2021
Same author

Discovery of a novel RORγ antagonist with skin-restricted exposure for topical treatment of mild to moderate psoriasis.

Scientific reports·2021
Same author

Turning-on persistent luminescence out of chromium-doped zinc aluminate nanoparticles by instilling antisite defects under mild conditions.

Nanoscale·2021
Same author

The α2-Plasmin Inhibitor-Plasmin Complex is a Potential Biomarker of Venous Thromboembolism in Orthopedic Trauma Patients.

Clinical laboratory·2021
Same author

Incidence, clinical risk and prognostic factors for liver metastasis in patients with cervical cancer: a population-based retrospective study.

BMC cancer·2021
Same author

Application of logistic regression and convolutional neural network in prediction and diagnosis of high-risk populations of lung cancer.

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)·2021

Related Experiment Video

Updated: Apr 20, 2026

Comparative Study on the Polysaccharide Contents and Antioxidant Activities of Hippophae rhamnoides subsp. sinensis and Hippophae gyantsensis
10:03

Comparative Study on the Polysaccharide Contents and Antioxidant Activities of Hippophae rhamnoides subsp. sinensis and Hippophae gyantsensis

Published on: August 15, 2025

989

LPs-1a: A hypoglycemic pectic polysaccharide from lemon peel - isolation, structural characterization, and activity

Meng Xi1, Yakun Hou2, Zhonggui Jiang1

  • 1College of Biology and Food Engineering, Chongqing Sanxia University of Science and Technology, Wanzhou, 404100, China.

International Journal of Biological Macromolecules
|April 18, 2026
PubMed
Summary
This summary is machine-generated.

A novel pectin from lemon peel waste, LPs-1a, shows promise for managing type 2 diabetes. This natural compound enhances glucose uptake and insulin secretion, offering a sustainable functional food ingredient.

Keywords:
Histidine metabolismHypoglycemic activityLemon peel polysaccharideLow-methoxyl pectinRG-I domainsStructural characterization

More Related Videos

Structural Characterization of Mannan Cell Wall Polysaccharides in Plants Using PACE
11:06

Structural Characterization of Mannan Cell Wall Polysaccharides in Plants Using PACE

Published on: October 16, 2017

10.3K
OLIgo Mass Profiling OLIMP of Extracellular Polysaccharides
08:43

OLIgo Mass Profiling OLIMP of Extracellular Polysaccharides

Published on: June 20, 2010

14.3K

Related Experiment Videos

Last Updated: Apr 20, 2026

Comparative Study on the Polysaccharide Contents and Antioxidant Activities of Hippophae rhamnoides subsp. sinensis and Hippophae gyantsensis
10:03

Comparative Study on the Polysaccharide Contents and Antioxidant Activities of Hippophae rhamnoides subsp. sinensis and Hippophae gyantsensis

Published on: August 15, 2025

989
Structural Characterization of Mannan Cell Wall Polysaccharides in Plants Using PACE
11:06

Structural Characterization of Mannan Cell Wall Polysaccharides in Plants Using PACE

Published on: October 16, 2017

10.3K
OLIgo Mass Profiling OLIMP of Extracellular Polysaccharides
08:43

OLIgo Mass Profiling OLIMP of Extracellular Polysaccharides

Published on: June 20, 2010

14.3K

Area of Science:

  • Food Science and Technology
  • Biochemistry
  • Nutraceuticals

Background:

  • Growing demand for natural functional food ingredients for type 2 diabetes (T2DM) management.
  • Need for sustainable utilization of agricultural by-products like lemon peel waste.

Purpose of the Study:

  • To investigate the hypoglycemic potential and mechanisms of a novel pectic polysaccharide (LPs-1a) from lemon peel waste.
  • To explore LPs-1a as a natural candidate for T2DM management.

Main Methods:

  • Structural characterization of LPs-1a (low-methoxyl RG-I-rich pectin).
  • Assessment of LPs-1a's effect on glucose uptake and insulin secretion in a Min6 pancreatic β-cell injury model.
  • Metabolomic analysis to elucidate LPs-1a's regulatory pathways.

Main Results:

  • LPs-1a demonstrated significant enhancement of glucose uptake and insulin secretion at 200 μg/mL.
  • Metabolomic analysis revealed histidine metabolism as a key pathway for LPs-1a's cellular repair function.
  • Established a structure-activity relationship for lemon peel-derived polysaccharides.

Conclusions:

  • LPs-1a is a scientifically validated, natural compound with potential for T2DM management.
  • Highlights LPs-1a as a functional food ingredient, dietary supplement, or nutraceutical.
  • Demonstrates a high-value utilization strategy for lemon peel waste, promoting health and sustainability.