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Collaborative Latin American Imaging Network In Neuroimmunology Research (BRAIMS): Rationale, Structure, Challenges,

Edgar Carnero Contentti1, Ricardo Alonso2, Vinícius Boldrini3

  • 1Neuroimmunology Unit, Department of Neurosciences, Hospital Alemán, Buenos Aires, Argentina; CENRos, Neuroimmunology Clinic, INECO Neurociencias Oroño, Rosario, Argentina.

Multiple Sclerosis and Related Disorders
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PubMed
Summary
This summary is machine-generated.

The Collaborative Latin American Imaging Network in Neuroimmunology Research (BRAIMS) addresses MRI variability in diagnosing neuroimmunological diseases across Latin America. This network aims to standardize imaging practices, improve diagnostic accuracy, and generate region-specific evidence for better patient care.

Keywords:
LATAMMOGADMultiple sclerosisNMOSDNeurimaging

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Area of Science:

  • Neuroimmunology
  • Neuroradiology
  • Medical Imaging

Background:

  • Magnetic resonance imaging (MRI) is crucial for diagnosing and monitoring neuroimmunological disorders like multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD).
  • Significant variability in healthcare systems, imaging infrastructure, protocols, and expertise in Latin America (LATAM) hinders standardized MRI approaches, leading to diagnostic heterogeneity.
  • Existing disparities in MRI access and advanced imaging techniques further complicate accurate diagnosis and research in the region.

Purpose of the Study:

  • To establish the Collaborative Latin American Imaging Network in Neuroimmunology Research (BRAIMS) to strengthen MRI research and clinical practice for neuroimmunological diseases in LATAM.
  • To promote methodological alignment, facilitate multicenter research, and generate region-specific real-world evidence.
  • To address challenges of unequal access, limited advanced techniques, and interpretation variability in LATAM neuroimaging.

Main Methods:

  • Formation of a collaborative network integrating core and collaborating centers across multiple LATAM countries.
  • Development of a coordinated governance model for shared research agendas and collaborative projects.
  • Prioritization of mapping MRI availability/practices, standardizing protocols, identifying variability sources, and developing consensus recommendations for resource-variable settings.

Main Results:

  • BRAIMS has been established as a regional initiative fostering collaboration among neuroimmunologists, neuroradiologists, and researchers.
  • The network is actively working on mapping current MRI practices and identifying key areas for standardization.
  • Initial efforts focus on developing region-specific recommendations tailored to diverse healthcare settings within LATAM.

Conclusions:

  • BRAIMS represents a significant step towards standardized MRI use in neuroimmunology across LATAM.
  • The network aims to improve diagnostic accuracy and enhance research capacity by generating context-specific evidence.
  • This initiative has the potential to reduce disparities in neuroimaging access and contribute to global neuroimmunology research.