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Updated: Apr 20, 2026

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Full Endoscopic Interlaminar Approach for Paracentral L5-S1 Disc Herniation
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Paralyzing herniated disc: To operate or not to operate, and when is the right time?
Keyvan Mostofi1, Kamran Shirbache2, Ali Shirbacheh3
1Centre Clinical, Department of Neurosurgery, centre clinical, Soyaux, France.
Injury
|April 18, 2026
Summary
Paralyzing disc herniation (PDH) after surgery affects over 7% of patients, with age and obesity as key risks. Further research is vital for effective management strategies.
Area of Science:
- Neurosurgery
- Spinal Surgery
- Neurology
Background:
- Paralyzing disc herniation (PDH) is a significant postoperative complication following lumbar disc herniation surgery.
- Limited research exists on PDH due to patient recruitment challenges and methodological variability.
Purpose of the Study:
- Investigate the mechanisms, risk factors, and conditions leading to PDH after L4-L5 disc herniation surgery.
- Address the lack of consensus on optimal management strategies for PDH.
Main Methods:
- Retrospective analysis of 1285 patients undergoing disc herniation surgery over ten years.
- Identified PDH incidence and associated risk factors.
Main Results:
- The incidence of PDH was 7.69% in the studied cohort.
- Key risk factors identified include advanced age, obesity, diabetes mellitus, narrow lumbar canal, and trauma.
- Observed a recovery rate of 66.66%, consistent with existing literature.
Conclusions:
- A significant knowledge gap exists regarding PDH pathophysiology and optimal postoperative management.
- The timing of intervention for PDH remains unclear, except in emergency cases.
- Further prospective research is essential to develop definitive management protocols for PDH.

