Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Reduction of Alkenes: Asymmetric Catalytic Hydrogenation

Reduction of Alkenes: Asymmetric Catalytic Hydrogenation

Catalytic hydrogenation of alkenes is a transition-metal catalyzed reduction of the double bond using molecular hydrogen to give alkanes. The mode of hydrogen addition follows syn stereochemistry.
The metal catalyst used can be either heterogeneous or homogeneous. When hydrogenation of an alkene generates a chiral center, a pair of enantiomeric products is expected to form. However, an enantiomeric excess of one of the products can be facilitated using an enantioselective reaction or an...

Cycloaddition Reactions: Overview

Cycloaddition Reactions: Overview

Cycloadditions are one of the most valuable and effective synthesis routes to form cyclic compounds. These are concerted pericyclic reactions between two unsaturated compounds resulting in a cyclic product with two new σ bonds formed at the expense of π bonds. The [4 + 2] cycloaddition, known as the Diels–Alder reaction, is the most common. The other example is a [2 + 2] cycloaddition.

Reduction of Alkynes to cis-Alkenes: Catalytic Hydrogenation

Reduction of Alkynes to cis-Alkenes: Catalytic Hydrogenation

Introduction
Like alkenes, alkynes can be reduced to alkanes in the presence of transition metal catalysts such as Pt, Pd, or Ni. The reaction involves two sequential syn additions of hydrogen via a cis-alkene intermediate.

Reduction of Benzene to Cyclohexane: Catalytic Hydrogenation

Reduction of Benzene to Cyclohexane: Catalytic Hydrogenation

Unlike the easy catalytic hydrogenation of an alkene double bond, hydrogenation of a benzene double bond under similar reaction conditions does not take place easily. For example, in the reduction of stilbene, the benzene ring remains unaffected while the alkene bond gets reduced. Hydrogenation of an alkene double bond is exothermic and a favorable process. In contrast, to hydrogenate the first unsaturated bond of benzene, an energy input is needed; that is, the process is endothermic. This is...

Heterogeneous Catalysis

Heterogeneous Catalysis

Heterogeneous catalysis involves a catalyst in a different phase from the reactants. It is a process where the catalyst and the reactants are in distinct phases, typically solid and gas or liquid.Most heterogeneous catalysts are metals, metal oxides, or acids. The list includes transition metals like iron (Fe), cobalt (Co), nickel (Ni), palladium (Pd), platinum (Pt), chromium (Cr), manganese (Mn), tungsten (W), silver (Ag), and copper (Cu). These metals possess partially vacant d orbitals that...

Reduction of Alkenes: Catalytic Hydrogenation

Reduction of Alkenes: Catalytic Hydrogenation

Alkenes undergo reduction by the addition of molecular hydrogen to give alkanes. Because the process generally occurs in the presence of a transition-metal catalyst, the reaction is called catalytic hydrogenation.
Metals like palladium, platinum, and nickel are commonly used in their solid forms — fine powder on an inert surface. As these catalysts remain insoluble in the reaction mixture, they are referred to as heterogeneous catalysts.
The hydrogenation process takes place on the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

High Entropy Metal Organic Framework Incorporated 2D Ti<sub>3</sub>C<sub>2</sub>T<sub>X</sub> MXene for Supercapacitor Application.

Chemistry, an Asian journal·2026

Same author

Vascular smooth muscle cell mechanotransduction: Pathways, phenotypes and emerging technologies.

The Journal of physiology·2026

Same author

PPM1B utilizes a trinuclear metal architecture for phosphatase activity.

bioRxiv : the preprint server for biology·2026

Same author

Atomically Precise [Cu-Cu<sub>54</sub>] Nanocluster-Catalyzed Three-Component Borylative Coupling of Alkynes with Alkyl Bromides and Chlorides.

Angewandte Chemie (International ed. in English)·2026

Same author

Mitochondrial DNA Instability and Neuroinflammation: Connecting the Dots Between Base Excision Repair and Neurodegenerative Disease.

Genes·2026

Same author

Cyclometalated Ru(II) Complexes Derived from Dibasic CNO Pincer Ligands as Molecular Catalysts for Electrocatalytic Hydrogen Evolution in Alkaline Medium.

Inorganic chemistry·2026

Search research articles

Related Experiment Video

Updated: Apr 21, 2026

Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units

Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units

Published on: September 18, 2016

Recent Advances in Heterogeneous Copper(0) Catalysis: Strategies for Cycloaddition, C-B Bond Formation, and Selective

Aishwarya Prakash¹, Sanjay Jagannatha¹, K Pramoda¹

¹Centre for Nano and Material Sciences (CNMS), JAIN (deemed to be University), Bangalore, India.

|April 19, 2026

Summary

Metallic copper nanoparticles (Cu(0) materials) synthesis is crucial for catalysis. This review details synthetic strategies and their use in organic transformations, covering advancements from 2016-2025.

Keywords:

characterization heterogeneous catalyst metallic copper nanoparticles organic transformation

More Related Videos

[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst

[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst

Published on: May 21, 2019

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions

Published on: November 30, 2022

Related Experiment Videos

Last Updated: Apr 21, 2026

Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units

Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units

Published on: September 18, 2016

[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst

[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst

Published on: May 21, 2019

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions

Published on: November 30, 2022

Area of Science:

Materials Science
Catalysis
Nanotechnology

Background:

Metallic copper nanoparticles (NPs) are of significant interest due to their catalytic properties.
Controlling NP size, shape, and stability is key for effective applications.
Recent advancements focus on optimizing synthetic procedures for Cu(0) materials.

Purpose of the Study:

To review various strategies for synthesizing metallic copper nanoparticles (Cu(0) materials).
To highlight the catalytic applications of these Cu(0) materials in organic synthesis.
To provide insights into recent developments (2016-2025) in the field.

Main Methods:

Summarizing diverse synthetic protocols for Cu(0) materials.
Analyzing variations in temperature, stoichiometry, and capping agents.
Compiling recent literature on synthesis and catalytic applications.

Main Results:

Detailed discussion of synthetic protocols for Cu(0) materials.
Overview of catalytic applications including C-N and C-B bond formation, nitroarene reduction, hydrogenation, and cyclization.
Identification of key developments in the field from 2016 to 2025.

Conclusions:

The review provides valuable insights into the synthesis and catalytic applications of Cu(0) materials.
Further advancements in Cu(0) material development and application are anticipated.
This work serves as a comprehensive resource for researchers in synthetic organic chemistry and catalysis.