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Cemento-ossifying fibroma: A South American multicenter study.
F-V-P Cobra1, É-O Santos, M Villarroel-Dorrego
1Department of Oral Diagnosis and Pathology School of Dentistry, Universidade Federal do Rio de Janeiro R. Rodolpho Paulo Rocco, n. 325, 1st floor Cidade Universitária, Rio de Janeiro, 21.941-902. RJ, Brazil augustodelima33@hotmail.com.
Cemento-ossifying fibroma (COF) is a benign tumor affecting the jaw. This study characterized COF in South America, finding it most common in women and the lower jaw, with surgical removal being the primary treatment.
Area of Science:
- Oral Pathology
- Odontogenic Neoplasms
- Fibro-osseous Lesions
Background:
- Cemento-ossifying fibroma (COF) is a benign fibro-osseous neoplasm.
- Characterized by proliferation of cellular fibrous stroma.
Purpose of the Study:
- To characterize the clinicodemographic, radiographic, and therapeutic profile of COF.
- First multicenter study of COF in South America.
Main Methods:
- Retrospective analysis of 112 COF cases from Brazil, Colombia, and Venezuela.
- Data collected from oral pathology and oral medicine services.
- Diagnoses based on WHO classification; data analyzed descriptively.
Main Results:
- Predominantly affected females (86.6%) aged 35.6±12.6 years.
- Posterior mandible was the most common site (65.3%).
- Mixed radiographic patterns and cortical expansion were frequent; surgical removal was the main treatment.
Conclusions:
- Confirms predilection for women and posterior mandible.
- Highlights subtle clinicodemographic variations across South American countries.
- Provides essential data on COF in the region.
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