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Related Experiment Video

Updated: Apr 21, 2026

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TPDPM: Text promptable diffusion probabilistic model for referring surgical instrument segmentation.

Jiale Guan1, Xiaoyang Zou1, Simeng Luo1

  • 1Institute of Medical Robotics, School of Biomedical Engineering, Shanghai Jiao Tong University, No. 800, Dongchuan Road, Shanghai, 200240, China.

Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society
|April 19, 2026
PubMed
Summary
This summary is machine-generated.

This study introduces a novel Text Promptable Diffusion Probabilistic Model (TPDPM) for referring surgical instrument segmentation (RSIS). TPDPM achieves superior performance and generalization by treating RSIS as a mask generation task, enhancing robotic surgery systems.

Keywords:
Diffusion probabilistic modelReferring surgical instrument segmentationRobot-assisted surgeryVisual-textual conditioning

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Area of Science:

  • Computer Vision
  • Medical Image Analysis
  • Robotics

Background:

  • Referring surgical instrument segmentation (RSIS) is crucial for context-aware computer-assisted interventions.
  • Existing RSIS methods rely on discriminative per-pixel classification.
  • Diffusion probabilistic models show promise in segmentation tasks.

Purpose of the Study:

  • To propose a novel Text Promptable Diffusion Probabilistic Model (TPDPM) for RSIS.
  • To formulate RSIS as a mask generation task conditioned on images and text.
  • To enable target-specific segmentation and uncertainty assessment in robotic surgery.

Main Methods:

  • Developed TPDPM, a generative model for RSIS.
  • Formulated RSIS as a mask generation task using a reverse diffusion process.
  • Utilized ensembling of network predictions for accuracy and uncertainty estimation.

Main Results:

  • TPDPM achieved superior RSIS performance compared to state-of-the-art methods.
  • Demonstrated competitive generalization capabilities across diverse datasets.
  • Successfully handled ambiguous instrument boundaries through stochastic sampling.

Conclusions:

  • TPDPM offers a novel and effective approach to RSIS.
  • The method enhances interactive capabilities for robot-assisted surgery.
  • TPDPM provides accurate segmentation and uncertainty assessment for surgical instruments.