Related Experiment Video
Updated: Apr 21, 2026

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
Published on: June 14, 2021
Unusual closure of a large traumatic macular hole after an unorthodox pars plana vitrectomy
H Hamdy Ghoraba1, M A Abdel Hafez2, A H Hamdi Ghoraba3
1Ophthalmology Department, Faculty of Medicine, Tanta University, Tanta, Egypt; Retina Department, Magrabi Eye Hospital, Tanta, Egypt.
Abstract:
This retrospective case report describes the closure of a large traumatic macular hole following PPV, posterior hyaloid detachment, and air tamponade despite the inability to perform ILM surgery. An 11-year-old male presented with a full-thickness macular hole following blunt trauma and a BCVA of counting fingers. Serial OCT examination precluded spontaneous closure. The surgery consisted of PPV and induction of posterior hyaloid detachment. All attempts to perform a modified ILM flap technique failed. Air tamponade was used at the end of the surgery. The post-operative OCT images showed U-type closure of the hole. The BCVA improved to 6/60. We recommend a modified ILM flap technique in large full-thickness traumatic macular holes to improve the functional and anatomical outcomes. Despite the inability of ILM surgery, the hole closure described in this report is an unusual finding.
Related Concept Videos
Angle Closure Glaucoma: Treatment
Glaucoma: Overview
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...

