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Cardiovascular Involvement in Autoimmune Rheumatic Diseases: Evaluation Using Cardiovascular MR Imaging

George Markousis-Mavrogenis1, George D Kitas2, Petros P Sfikakis3

  • 1Department of Cardiology, Angiology and Pneumology, Heidelberg University, Heidelberg, Germany; German Centre for Cardiovascular Research (DZHK), Partner Site Heidelberg/Mannheim, Heidelberg, Germany; Cardiovascular Magnetic Resonance Unit, University Research Institute of Maternal and Child Health and Precision Medicine and UNESCO (United Nations Educational, Scientific and Cultural Organization) Chair in Adolescent Healthcare, Medical School, National and Kapodistrian University of Athens, Aghia Sophia Children's Hospital, Athens, Greece.

Magnetic Resonance Imaging Clinics of North America
|April 19, 2026
PubMed

Insights

Cardiovascular disease (CVD) causes one-third of deaths in autoimmune rheumatic diseases (ARDs). Cardiovascular magnetic resonance (CMR) is an ideal noninvasive tool for diagnosing and monitoring various forms of CVD in ARD patients.

Area of Science:

  • Cardiology
  • Rheumatology
  • Medical Imaging

Background:

  • Cardiovascular disease (CVD) accounts for a significant portion of mortality in patients with autoimmune rheumatic diseases (ARDs).
  • CVD in ARDs encompasses a spectrum of conditions including coronary artery disease, inflammatory cardiomyopathy, heart failure, and valvular heart disease.

Purpose of the Study:

  • To highlight the critical role of cardiovascular magnetic resonance (CMR) in the diagnosis and management of CVD in patients with ARDs.

Main Methods:

  • Review of the utility of Cardiovascular Magnetic Resonance (CMR) for evaluating cardiovascular complications in autoimmune rheumatic diseases.
  • Utilizing both established and novel parametric indices provided by CMR.

Main Results:

  • Cardiovascular magnetic resonance (CMR) offers comprehensive functional and tissue characterization, making it suitable for diagnosing and monitoring CVD in ARDs.
  • CMR provides essential data for assessing macro- and microvascular coronary artery disease, inflammatory cardiomyopathy, heart failure, valvular heart disease, and non-coronary vascular disease.

Conclusions:

  • Cardiovascular magnetic resonance (CMR) is a powerful, noninvasive imaging modality for the cardiovascular evaluation of patients with autoimmune rheumatic diseases.
  • CMR's capabilities support its role in the diagnosis and follow-up of diverse cardiovascular manifestations in ARDs.

Keywords:
Coronary artery diseaseMyocarditisPericarditisSystemic inflammatory diseasesValvular heart disease

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