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Cardiovascular Magnetic Resonance in Detecting Cardiovascular Involvement in Systemic Inflammatory Disease: Focus on
Planinka Zafirovska1, Viseslav Popadic2, Maja Popovic3
1Department of Imaging, University Hospital Medical Center Bezanijska Kosa, Belgrade, Serbia; Department of Internal Medicine, Faculty of Medical Sciences, University "Goce Delchev", Stip, North Macedonia.
Insights
Chronic systemic inflammation contributes to heart disease. Cardiovascular magnetic resonance (CMR) detects early cardiac damage in inflammatory conditions like IBD, obesity, and scleroderma, offering better specificity than current biomarkers.
Area of Science:
- Cardiology
- Immunology
- Radiology
Background:
- Chronic systemic inflammation is linked to cardiovascular disease, autoimmune disorders, and metabolic syndromes.
- Existing biomarkers for myocardial injury lack specificity and cannot detect localized cardiac damage.
- There is a need for advanced imaging biomarkers to identify early cardiac involvement in systemic diseases.
Purpose of the Study:
- To review the utility of Cardiovascular Magnetic Resonance (CMR) in diagnosing cardiac involvement in systemic inflammatory diseases.
- To highlight CMR's role in evaluating myocardial injury and inflammation.
- To focus on the application of CMR in inflammatory bowel disease, obesity, and systemic sclerosis.
Main Methods:
- Review of current literature on CMR applications in systemic inflammatory diseases.
- Analysis of studies demonstrating CMR's ability to detect myocardial inflammation and injury.
- Focus on specific inflammatory conditions: inflammatory bowel disease, obesity, and systemic sclerosis.
Main Results:
- CMR is a powerful, safe imaging modality for comprehensive cardiac evaluation.
- CMR can detect early cardiac involvement and localized myocardial damage in systemic inflammation.
- CMR provides superior diagnostic information compared to traditional biomarkers for cardiac assessment.
Conclusions:
- Cardiovascular magnetic resonance is crucial for assessing cardiac complications in systemic inflammatory diseases.
- CMR enables early detection of myocardial injury, improving patient management.
- The review underscores CMR's value in understanding the cardiac impact of inflammatory bowel disease, obesity, and systemic sclerosis.
Abstract:
Chronic systemic inflammation is increasingly recognized as a key contributor to cardiovascular disease, autoimmune disorders, and metabolic syndromes. Systemic inflammatory conditions share common pathophysiological pathways leading to myocardial injury, and biomarkers. However, these markers lack specificity and offer no information on localized myocardial damage, underscoring the need for advanced imaging biomarkers capable of detecting early cardiac involvement. Cardiovascular magnetic resonance (CMR) has emerged as a powerful and safe modality for comprehensive cardiac evaluation. This review summarizes the role of CMR in detecting cardiac involvement in systemic inflammatory diseases, focusing on inflammatory bowel disease, obesity, and systemic sclerosis.
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