Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cardiopulmonary Resuscitation III: AED Use01:23

Cardiopulmonary Resuscitation III: AED Use

Introduction to AEDAn Automated External Defibrillator (AED) is a portable medical device that analyzes the heart's rhythm and, if necessary, delivers an electrical shock to help the heart re-establish an effective rhythm during sudden cardiac arrest (SCA). SCA occurs when the heart suddenly and unexpectedly stops beating, leading to a loss of blood flow to the brain and other vital organs. In such emergencies, time is of the essence, and using an AED, combined with Cardiopulmonary...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Transvenous Aorticorenal Ganglion Stimulation in Humans.

Hypertension (Dallas, Tex. : 1979)·2026
Same author

Accuracy of a Deep Learning Model in Intracardiac Echocardiography.

JACC. Advances·2026
Same author

Plasma proteomics and coronary artery calcium score: synergistic, concordant and contrasting predictions of cardiovascular outcomes in The Multi-Ethnic Study of Atherosclerosis.

medRxiv : the preprint server for health sciences·2026
Same author

Intracardiac echocardiography from the left heart chambers to guide electrophysiology procedures.

Heart rhythm·2026
Same author

Optimal pace timing for left bundle branch area pacing with or without an additional LV lead: results from the CSPOT study.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology·2026
Same author

Integrating Genomics and Proteomics to Identify Causal Proteins and Biologic Pathways for Incident Atrial Fibrillation in CKD.

Journal of the American Society of Nephrology : JASN·2026

Related Experiment Video

Updated: Jun 14, 2026

A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation
16:40

A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation

Published on: February 28, 2012

27.0K

Quantitative Vector Screening to Improve Sensing and Reduce Inappropriate Shocks With the Subcutaneous Implantable

Thomas A Boyle1, David C Callans1, Rajat Deo1

  • 1Cardiovascular Division, Perelman School of Medicine at the University of Pennsylvania, Philadelphia.

Circulation. Arrhythmia and Electrophysiology
|April 20, 2026
PubMed
Summary

A new quantitative vector screening (QVS) protocol for subcutaneous implantable cardioverter-defibrillators (S-ICD) significantly reduced inappropriate shocks. This improved S-ICD patient safety by optimizing device implantation criteria.

Keywords:
defibrillatorsincidencepatient selectionsurvival analysis

More Related Videos

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
06:10

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Published on: June 12, 2021

3.8K
Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease
06:16

Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease

Published on: August 9, 2024

1.1K

Related Experiment Videos

Last Updated: Jun 14, 2026

A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation
16:40

A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation

Published on: February 28, 2012

27.0K
Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
06:10

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Published on: June 12, 2021

3.8K
Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease
06:16

Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease

Published on: August 9, 2024

1.1K

Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Medical Devices

Background:

  • Subcutaneous Implantable Cardioverter Defibrillators (S-ICD) provide protection against sudden cardiac death without transvenous leads.
  • Despite advancements, inappropriate shocks remain a concern in certain patient populations.
  • Optimizing S-ICD implantation screening is crucial for patient safety and device efficacy.

Purpose of the Study:

  • To evaluate the impact of a novel quantitative vector screening (QVS) protocol on sensing-related complications and inappropriate shocks in S-ICD patients.
  • To assess if QVS improves patient selection for S-ICD implantation compared to traditional methods.
  • To analyze the incidence of inappropriate shocks and other device-related issues post-QVS implementation.

Main Methods:

  • A retrospective analysis of 223 consecutive S-ICD implantations was conducted.
  • Patients were divided into two groups: traditional vector screening (pre-2023) and QVS protocol (2023 onwards).
  • QVS incorporated quantitative sensing scores, raising implantation thresholds. Primary endpoint: time to first inappropriate shock or under-sensed ventricular arrhythmia. Survival analyses were used.

Main Results:

  • The QVS protocol reduced patient eligibility for S-ICD implantation from 96% to 83% during pre-implant screening.
  • Patients in the QVS arm experienced significantly fewer primary endpoint events (1.8 per 100 patient-years) compared to the traditional screening arm (5.2 per 100 patient-years) (log-rank, P=0.02).
  • Median follow-up was 42 months for traditional screening and 18 months for QVS, with QVS showing a longer time to the primary endpoint.

Conclusions:

  • Implementing the QVS protocol for S-ICD screening, with stricter eligibility criteria, effectively reduced sensing-related complications.
  • The QVS protocol demonstrated a significant decrease in inappropriate shocks, enhancing patient safety.
  • This novel screening method offers a promising approach to optimize S-ICD implantation and minimize adverse events.