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Abdominal Organ Transplantation: Noteworthy Literature in 2025
Akira Katayama1,2, Marc Casale3, Rob Huseby3
1Department of Anesthesiology and Resuscitology, Okayama University Hospital, Okayama, Japan.
Seminars in Cardiothoracic and Vascular Anesthesia
|April 20, 2026
Summary
This review covers 2025 literature for abdominal organ transplantation, focusing on kidney, pancreas, liver, and intestinal transplants. Key areas include machine perfusion, pain management, and sarcopenia
Area of Science:
- Anesthesiology
- Critical Care Medicine
- Transplantation Surgery
Background:
- Abdominal organ transplantation is a complex procedure requiring specialized perioperative care.
- Continuous advancements in transplantation necessitate regular reviews of pertinent literature.
- Anesthesiologists and critical care physicians play a vital role in managing these complex patients.
Purpose of the Study:
- To review and highlight significant literature published in 2025 relevant to abdominal organ transplantation.
- To provide an overview of recent research in kidney, pancreas, liver, and intestinal transplantation.
- To identify key emerging trends and areas of focus in the field.
Main Methods:
- Comprehensive literature search of peer-reviewed publications and clinical trials from 2025.
- Focused review of studies related to kidney, pancreas, liver, and intestinal transplantation.
- Categorization of research based on transplantation type and key themes.
Main Results:
- 19 studies reviewed for kidney transplantation (from 5334 publications).
- 4 studies reviewed for pancreas transplantation (from 2231 publications).
- 4 studies reviewed for intestinal transplantation (from 2162 publications).
- 28 studies reviewed for liver transplantation (from 4925 clinical trials).
- Key research areas identified: machine perfusion (kidney/liver), pain management (donor/recipient), and impact of sarcopenia on liver transplant outcomes.
Conclusions:
- The 2025 literature demonstrates significant progress in abdominal organ transplantation.
- Machine perfusion technologies are advancing for kidney and liver grafts.
- Further research is needed on optimizing pain management and understanding the impact of patient factors like sarcopenia on transplant success.
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