Treatment options for dogs diagnosed with sinonasal aspergillosis

In dogs diagnosed with sinonasal aspergillosis (SNA) does inclusion of debridement in the treatment protocol improve clinical outcomes compared to dogs treated without debridement?

Treatment.

No papers that directly addressed the PICO were reviewed. Four retrospective case series which partially addressed the PICO question were discussed in the appraisal.

Zero.

None.

No conclusions can be made based on the current level of evidence, however the studies discussed in the appraisal suggest that there may be an association between the inclusion of debridement in the treatment protocol for SNA and an improved clinical outcome. Undertaking further higher-level studies (comparative, blind, prospective, randomised) would be required to confirm this. Ethical implications would not preclude such studies, for there is evidence that treatment protocols including topical deposition of antifungal agents alone are efficacious.