Intravitreal Bevacizumab plus Methotrexate for iris and ciliary body metastasis from lung cancer
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Published on: October 27, 2014
Thaís Marino de Azeredo Bastos1, Igor Neves Coelho1, Leticia Audi1
1Departments of Ophthalmology, Ribeirão Preto School of Medicine, University of São Paulo, Ribeirão Preto, Brazil.
Purpose:
To describe a case of iris and ciliary body metastasis from lung adenocarcinoma responding to intravitreal bevacizumab and methotrexate.
Observations:
A 66-year-old man presented with an amelanotic vascular lesion of the iris and ciliary body (7 × 4 mm, 4 mm thick). Fine-needle aspiration biopsy confirmed lung adenocarcinoma. After intravitreal bevacizumab and methotrexate, the tumor showed marked regression within 2 months.
Conclusions:
Intravitreal bevacizumab combined with methotrexate may represent a minimally invasive alternative to radiation therapy for ocular metastases.
