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COVID-19-Associated Cardiovascular Complications: A Narrative Literature Review
Aashna Lala1, Mykhailo Vysochyn2, Kateryna Shyshkova2
1Clinical Sciences, Saint James School of Medicine, Park Ridge, USA.
Insights
Coronavirus disease 2019 (COVID-19) is a systemic illness impacting the heart, causing complications like heart failure and arrhythmias. This review details cardiovascular issues in COVID-19 patients, aiding clinical recognition and management.
Area of Science:
- Cardiology
- Infectious Diseases
- Public Health
Background:
- Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, is a global health crisis.
- Initially viewed as respiratory, COVID-19 is now recognized as a systemic disease with significant cardiovascular implications.
- Cardiovascular complications affect both patients with and without pre-existing heart conditions.
Purpose of the Study:
- To review current evidence on cardiovascular complications in adult COVID-19 patients in the U.S.
- To highlight differences in cardiovascular pathology between those with and without prior cardiovascular disease.
- To discuss mechanisms, clinical features, diagnostics, and management of COVID-19-related cardiovascular issues.
Main Methods:
- This study is a narrative review of existing literature.
- Focuses on adult patients diagnosed with COVID-19 in the United States.
- Synthesizes evidence regarding cardiovascular manifestations and outcomes.
Main Results:
- COVID-19 can lead to myocardial injury, myocarditis, heart failure, arrhythmias, and thromboembolic events.
- These complications increase disease severity and mortality.
- Understanding these effects is crucial for patient management.
Conclusions:
- COVID-19 poses substantial cardiovascular risks, necessitating increased clinical awareness.
- Timely recognition and appropriate management are key to improving outcomes for affected patients.
- Further research into mechanisms and treatments is warranted.
Abstract:
Since the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 2019, coronavirus disease 2019 (COVID-19) has caused significant global morbidity and mortality. Although initially recognized as a respiratory illness, COVID-19 is now understood to be a systemic disease with substantial cardiovascular involvement. Both patients with pre-existing cardiovascular disease and those without prior cardiac conditions may develop a wide range of cardiovascular complications during and after acute infection. Reported complications include myocardial injury, myocarditis, heart failure, arrhythmias, and thromboembolic events, all of which contribute to increased disease severity and mortality. This narrative review summarizes current evidence on cardiovascular complications associated with COVID-19 among adult patients in the United States, with particular attention to differences between individuals with pre-existing cardiovascular disease and those who develop new cardiovascular pathology following SARS-CoV-2 infection. This review discusses proposed mechanisms of cardiovascular injury, clinical manifestations, diagnostic approaches, and current management strategies. By summarizing current knowledge, this review aimed to increase awareness of COVID-19-related cardiovascular complications, support timely recognition in emergency and inpatient settings, and assist clinicians in improving patient outcomes.
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