Evaluating the effect of equine tetanus antitoxin on mortality rates of dogs affected by tetanus

In dogs with tetanus, does administering the equine tetanus antitoxin compared to not administering the antitoxin reduce mortality rates?

Treatment.

Three studies were reviewed for this Knowledge Summary, all of which were retrospective case-control studies.

Weak.

There was no difference in survival to discharge between dogs treated and dogs not treated with equine tetanus antitoxin.

The current literature suggests that administering the equine tetanus antitoxin to dogs affected by tetanus had no positive or negative effect on mortality rates, though the level of evidence amongst the literature is weak.