Effect of Vitamin D3 Supplements in the Success of Dental Implants: A Comparative Evaluation

Dental implants are a reliable treatment for tooth replacement, with success dependent on osseointegration, implant stability, and bone density. Vitamin D3 plays a critical role in bone metabolism, influencing calcium absorption and bone mineralization. However, the effect of vitamin D3 supplementation on implant outcomes remains controversial.

A total of 20 patients with vitamin D deficiency (10-30 ng/mL) were divided into two groups:Group A (n = 10): Received vitamin D3 supplementation (60,000 IU/week for 8 weeks, followed by 60,000 IU/month for 16 weeks).Group B (n = 10): Did not receive supplementation.All patients underwent standard implant placement. Crestal bone level and bone density were assessed using CBCT, and implant stability was measured using resonance frequency analysis (RFA) at baseline, 3 months, and 6 months postimplant placement. Data were analyzed using ANOVA (P < 0.05).

Implant stability improved significantly in Group A compared with Group B at 3 and 6 months (P < 0.05). Crestal bone loss was higher in Group B, but the difference was not statistically significant (P = 0.07). Bone density remained comparable between both groups at all time points (P = 1.00).

Vitamin D3 supplementation significantly enhances implant stability, suggesting a role in improving early-stage osseointegration. However, its effect on crestal bone level and bone density remains inconclusive. Preoperative vitamin D3 screening and supplementation in deficient individuals may optimize implant outcomes. Further large-scale studies are needed to establish definitive guidelines.