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Characteristics and Effectiveness of Patient Navigation Programs on Colorectal Cancer Screening and Follow-Up
Meagan Pilar1, Sonja Hoover2, Jessica Roberson2
1RTI International, Research Triangle Park, North Carolina.
AJPM Focus
|April 20, 2026
Summary
Patient navigation significantly increases colorectal cancer screening rates by addressing patient barriers. Further research is needed to optimize implementation and maximize screening impact.
Area of Science:
- Public Health
- Health Services Research
- Cancer Prevention
Background:
- Patient navigation is an evidence-based strategy to overcome barriers and improve colorectal cancer screening rates.
- Understanding the implementation and effectiveness of navigation programs is crucial for optimizing their impact.
Purpose of the Study:
- To systematically review the implementation and effectiveness of patient navigation interventions for colorectal cancer screening.
- To identify factors influencing the success of navigation programs and inform future research and practice.
Main Methods:
- A systematic review of English-language articles published between 2004-2023, focusing on U.S. studies.
- Data extraction from 30 included studies, assessing study and intervention characteristics, and screening outcomes using the Cochrane Risk of Bias Tool (ROB 2).
- Adherence to PRISMA guidelines for systematic reviews.
Main Results:
- Thirty studies were included, with 29 reporting multicomponent interventions including patient navigation.
- Patient navigation interventions led to an average increase in screening uptake of 16.9 percentage points.
- Limited data were available on implementation outcomes.
Conclusions:
- Patient navigation is an effective strategy for enhancing colorectal cancer screening uptake.
- Further research on implementation outcomes is essential for optimizing screening impact, resource allocation, and equitable access.
- Improved understanding of implementation can lead to better patient outcomes.
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