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A Model to Simulate Clinically Relevant Hypoxia in Humans
Published on: December 22, 2016
Respiratory and oxygen saturation data for improved modelling and detection of obstructive sleep apnoea
Jordan F Hill1, Ella F S Guy1, Jaimey A Clifton1
1Department of Mechanical Engineering, University of Canterbury, Christchurch 8041, New Zealand.
None:
Twenty healthy adults (10 male, 10 female) participated in a data collection trial designed to capture arterial and venous pulsatile waveforms for oxygen saturation estimation, along with respiratory pressure and flow data to support modelling and prediction of obstructive sleep apnoea (OSA) events. Each participant completed eight one-minute tests while wearing a full-face mask connected to a custom inline pressure and flow sensor, with a Fisher & Paykel SleepStyle CPAP device setting postive PEEP levels at 0, 4, and 8 cmH₂O. A custom reflectance pulse oximeter was taped to the right side of the neck to capture pulsatile waveforms from the carotid artery and internal jugular vein, while a commercial BTIMOS sat801+ pulse oximeter recorded arterial oxygen saturation (SpaO₂) and heart rate from the right index finger. Test conditions included baseline breathing and simulated apnoeas involving 10- and 20-second breath-holds at each PEEP level. Ethical approval was granted by the University of Canterbury Human Research Ethics Committee (Ref: HREC 2024/163/LR-PS). This data aims to support improved apnoea detection, enabling better adaptive control of positive airway pressure (PAP) therapy based on oxygen saturation and respiratory signals.
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