Related Experiment Video
Updated: Apr 21, 2026

11:02
Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics
Published on: November 29, 2024
1.5K
[A malignant cause of metabolic decompensation]
Anja Forrer1,2, Mattia Giarrusso3, Rahel Wright4
1Klinik für Innere Medizin, Stadtspital Triemli, Zürich.
Praxis
|April 20, 2026
Summary
Incidental adrenal tumors are increasingly found. This case report highlights a rare, aggressive adrenal malignoma requiring thorough evaluation for malignancy and hormonal activity.
Area of Science:
- Endocrinology
- Oncology
- Radiology
Background:
- Computed tomography and magnetic resonance imaging reveal a rise in incidentally discovered adrenal tumors.
- Comprehensive evaluation of adrenal tumors for malignancy and hormonal function is crucial.
- This report details a rare case of a highly aggressive adrenal malignoma.
Purpose of the Study:
- To present a case of a rare adrenal malignoma.
- To emphasize the importance of evaluating incidentally found adrenal tumors.
Main Methods:
- Case report presentation.
- Review of diagnostic imaging (CT/MRI).
- Clinical and pathological assessment of the adrenal tumor.
Main Results:
- A rare adrenal malignoma was identified.
- The tumor exhibited aggressive characteristics.
Conclusions:
- Incidental adrenal tumors necessitate careful diagnostic workup.
- Rare and aggressive adrenal malignomas pose significant clinical challenges.
More Related Videos
Related Concept Videos
Diabetic Ketoacidosis ll: Pathophysiology
1
Diabetic ketoacidosis (DKA) is a metabolic emergency characterized by hyperglycemia, ketonemia, and metabolic acidosis. It results from severe insulin deficiency and an excess of counterregulatory hormones, leading to uncontrolled lipolysis, ketogenesis, and widespread electrolyte and fluid disturbances.Pathophysiology The central event in DKA is a profound loss of insulin action. Without insulin, glucose uptake in insulin-dependent tissues is impaired, while hepatic glucose production...
1
Diabetic Ketoacidosis l: Introduction
7
DefinitionDiabetic ketoacidosis (DKA) is an acute, life-threatening complication of diabetes mellitus, characterized by a triad of hyperglycemia (blood glucose >250 mg/dL), ketonemia or ketonuria, and metabolic acidosis (arterial pH <7.30 and serum bicarbonate <18 mEq/L). It results from insulin deficiency combined with elevated levels of counterregulatory hormones—glucagon, catecholamines, cortisol, and growth hormone—leading to increased lipolysis, hepatic...
7
Inborn Errors of Metabolism
1.1K
Phenylketonuria (PKU) is a protein metabolism disorder characterized by high blood levels of the amino acid phenylalanine. This results from a mutation in the gene responsible for phenylalanine hydroxylase, an enzyme that converts phenylalanine into tyrosine. When this enzyme is deficient, phenylalanine builds up in the blood, leading to symptoms such as vomiting, rashes, seizures, growth deficiency, and severe mental retardation. An early diagnosis and a diet restricting phenylalanine intake...
1.1K
Acute Respiratory Failure-III
1.2K
Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without...
1.2K
Complications of Diabetes Mellitus
6
Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia due to insulin deficiency, resistance, or both. Prolonged hyperglycemia disrupts metabolic homeostasis and leads to acute and chronic complications.Acute ComplicationsAcute complications result from sudden metabolic imbalance.Diabetic ketoacidosis (DKA) mainly appears in type 1 diabetes but may also develop in type 2 diabetes, particularly under extreme stress. It arises from severe insulin deficiency,...
6
Overview of Protein Metabolism
4.9K
Proteins are broken down into amino acids during digestion. Unlike fats and carbohydrates, which are stored for later use, proteins are not. Instead, amino acids are either used to produce ATP through oxidation or contribute to the creation of new proteins for the growth and repair of the body. Any surplus amino acids from the diet are converted into glucose or triglycerides rather than excreted.
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
4.9K

