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AQP1 is Involved in NLRP3-Related Microglial Polarization and Cognitive Impairment in Chronic Sleep Deprivation

Yanhong Xiong1,2, Weidong Liang3, Hong Zhu1,2

  • 1Department of Anesthesiology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.

Inflammation
|April 20, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
AQP1Chronic sleep deprivationCognitive dysfunctionMicroglial polarizationNLRP3 inflammasome

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Related Concept Videos

Aquaporins01:25

Aquaporins

Aquaporins or AQPs are a family of integral membrane proteins whose primary function is to transport water, while some called aquaglyceroporins also transport glycerol. In addition, aquaporins have also been suspected to be involved in transporting volatile substances, such as carbon dioxide and ammonia, across membranes. Such AQPs that act as gas channels are often highly expressed in cells involved in the gaseous exchange, such as red blood cells, epithelial cells, and pulmonary capillaries.