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Financial Hardship, End-of-Life Health Care Use, and Costs in Patients With Cancer
Veena Shankaran1,2,3,4, Li Li1, Sara Khor5
1Hutchinson Institute for Cancer Outcomes Research, Fred Hutch Cancer Center, Seattle, Washington.
JAMA Network Open
|April 20, 2026
Summary
Adverse financial events (AFEs) in cancer patients are linked to increased emergency department visits, hospitalizations, hospital deaths, and higher end-of-life care costs. Financial hardship impacts cancer care utilization and outcomes.
Area of Science:
- Oncology
- Health Economics
- Health Services Research
Background:
- Patients with cancer face a higher risk of adverse financial events (AFEs) compared to the general population.
- The impact of personal finances on cancer care, especially at the end of life (EOL), remains understudied.
Purpose of the Study:
- To investigate the association between AFEs and healthcare utilization and costs at the end of life among cancer patients.
Main Methods:
- A cohort study linked cancer registry data with commercial payer, Medicare claims, and credit records.
- Included patients with solid tumors (Stage I-IV) who died between 2013-2019.
- Compared healthcare use (ED, inpatient visits, place of death) and costs in the last 3-6 months of life between patients with and without new AFEs in the preceding two years.
Main Results:
- Patients with AFEs (8.6%) had significantly higher odds of multiple ED/inpatient visits (OR 1.41) and hospital death (OR 1.50).
- Mean adjusted healthcare costs were higher for patients with AFEs in the last 3 months ($35,115 vs $31,031) and 6 months ($57,401 vs $51,602) of life.
- Incremental costs in the AFE group were $4,084 (3 months) and $5,799 (6 months).
Conclusions:
- AFEs are associated with increased healthcare utilization, higher risk of inpatient death, and elevated care costs at the end of life for cancer patients.
- Findings suggest a need to explore interventions mitigating financial hardship to improve EOL care and reduce costs for cancer patients.
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