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Related Concept Videos

Peripheral Artery Disease IV: Nursing Management01:26

Peripheral Artery Disease IV: Nursing Management

676
 The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses,...
676
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

622
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
622
Pulmonary Edema II: Pathophysiology01:18

Pulmonary Edema II: Pathophysiology

17
Pulmonary edema is the accumulation of fluid in the interstitial and alveolar spaces of the lungs, impairing gas exchange and oxygen delivery. It may be cardiogenic or noncardiogenic, but both reduce oxygenation and lung compliance.Cardiogenic Pulmonary EdemaCardiogenic edema results from increased hydrostatic pressure in pulmonary capillaries, usually due to left ventricular dysfunction from myocardial infarction, heart failure, or valvular disease. Ineffective cardiac pumping causes blood to...
17
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

405
Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
405
Nephrotic Syndrome III : Nursing Management01:24

Nephrotic Syndrome III : Nursing Management

533
Nursing management for nephrotic syndrome adapts as the disease progresses, with strategies evolving to address advancing symptoms and complications.Early-Stage Management In the early stages, nursing interventions for nephrotic syndrome resemble those used in managing acute glomerulonephritis, focusing on symptom monitoring, fluid balance, and managing mild to moderate edema.Vital Signs: Regularly monitor blood pressure, pulse, respiratory rate, and temperature to promptly identify...
533
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

748
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
748

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Related Experiment Video

Updated: Apr 22, 2026

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Peripheral Edema in Advanced Cancer: Mechanisms and Management-A Scoping Review.

Jegy M Tennison1, Ekta Gupta Sharma1, Rachel Lee2

  • 1Department of Palliative, Rehabilitation, and Integrative Medicine, Section of Physical Medicine & Rehabilitation, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

Journal of Palliative Medicine
|April 21, 2026
PubMed
Summary

Peripheral edema in advanced cancer patients stems from varied causes. Mechanism-based treatments, like fluid management and stenting, offer short-term symptom relief, highlighting the need for individualized care.

Keywords:
diureticsedemafunctional statuslymphedemaneoplasmspalliative carephysical therapy modalitiesquality of lifesymptom burden

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Area of Science:

  • Oncology
  • Palliative Care
  • Medical Research Methodology

Background:

  • Peripheral edema is a frequent complication in advanced cancer, negatively impacting patient quality of life.
  • Causes extend beyond lymphatic issues, requiring a mechanism-based management strategy.
  • Existing research on peripheral edema in advanced cancer is limited.

Purpose of the Study:

  • To identify and characterize the causes of peripheral edema in advanced cancer.
  • To review current treatments and their outcomes for peripheral edema in this population.
  • To address knowledge gaps regarding peripheral edema management in advanced cancer.

Main Methods:

  • A five-step scoping review methodology was employed.
  • Searches included MEDLINE, Embase, and Cochrane Library (2010-2023).
  • Eligible studies involved adult patients with peripheral edema related to advanced cancer, its treatments, or comorbidities.

Main Results:

  • 31 studies (observational, case series, case reports) met inclusion criteria.
  • Identified causes included overhydration, malignant inferior vena cava obstruction, and multiple risk factors.
  • Mechanism-guided treatments like stenting, fluid management, and decongestive therapy showed short-term benefits.

Conclusions:

  • Peripheral edema in advanced cancer has diverse, overlapping causes.
  • Mechanism-based interventions can provide meaningful short-term symptom improvement.
  • Further standardized assessment and prospective studies are crucial for evidence-based, individualized care.