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Updated: Apr 23, 2026
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Biomechanical Characterization of Human Soft Tissues Using Indentation and Tensile Testing
Published on: December 13, 2016
33.9K
The PassTrue® technique for evaluating the needle/tissue mechanical interaction in a medicolegal simulation setting
Rafael Boscolo-Berto1,2, Martina Contran1,2, Alessandro De Cassai3,4
1Institute of Human Anatomy, Department of Neurosciences, University of Padova, Italy.
Summary
A new PassTrue® method accurately tracks needle trajectories in soft tissues using a coaxial thread. This technique enhances the assessment of needle-tissue interactions and iatrogenic damage in forensic clinical anatomy.
Area of Science:
- Forensic clinical anatomy
- Medical procedure analysis
- Biomechanical testing
Background:
- Body donations and reference centers enable ex vivo reproduction of needle-tissue interactions.
- Understanding iatrogenic damage from medical procedures is crucial.
Purpose of the Study:
- Develop a reproducible, standardized benchtop methodology.
- Identify the trajectory of needles piercing soft tissue.
- Detect iatrogenic tissue damage caused by needles.
Main Methods:
- Utilized skeletal muscle tissue from a fresh-frozen human donor.
- Developed the PassTrue® methodology involving coaxial thread insertion.
- Tested the technique against a control procedure without a thread.
Main Results:
- The PassTrue® technique successfully identified needle trajectories in 100% of tested cases.
- Microscopic analysis confirmed the needle's course using the thread.
- Control procedures without the thread showed no identifiable needle path.
Conclusions:
- The novel PassTrue® methodology efficiently assesses needle-tissue interactions.
- This technique allows for precise identification of needle trajectories within biological tissues.
- Improves understanding of iatrogenic effects in forensic and medical contexts.
