Related Experiment Video
Updated: Jul 1, 2026

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Gene-environment Interaction Models to Unmask Susceptibility Mechanisms in Parkinson's Disease
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Exercise-induced GPLD1 is associated with neuroprotection and improvement of hippocampal dysfunction in an
Muaz Belviranlı1, Nilsel Okudan2, Tuğba Sezer2
1School of Medicine, Department of Physiology, Selçuk University, Konya, 42131, Turkey. mbelviranli@yahoo.com.
Metabolic Brain Disease
|April 21, 2026
Abstract
No abstract available in PubMed .
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Long-term Potentiation
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Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
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Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
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Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
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