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Daniela Angelova-Toshkina1, Denny Schanze2, Pia Vaassen3

  • 1Pediatrics and Adolescent Medicine, Faculty of Medicine, University of Augsburg, Stenglinstr. 2, Augsburg, 86156, Germany.

Molecular and Cellular Pediatrics
|April 21, 2026
PubMed
Summary

No abstract available in PubMed .

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The Ras-gene-encoded proteins are regulators of signaling pathways controlling cell proliferation, differentiation, or cell survival. The Ras-gene family in humans constitutes three primary members—the HRas, NRas, and KRas. These genes code for four functionally distinct yet closely related proteins—the HRas, NRas, KRas4A, and KRas4B. The involvement of mutant Ras genes in human cancer was first discovered in 1982 and is among the most common causes of human tumorigenesis.
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