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Published on: August 1, 2019
Patient-reported outcomes and attitudes in patients at high-risk for breast cancer
Cassidy T Yoshida1, Madeline G Higgins2, Sarah E Leslie3
1School of Medicine, University of Colorado Anschutz Medical Center, 13001 E 17th Place, Aurora, CO, 80045, USA.
Background:
Quality of life is assessed using patient-reported outcome measures (PROMs), but is rarely utilized in patients at high risk for breast cancer despite greater distress. We evaluated PROMs in this population.
Methods:
Participants completed the BREAST-Q, measuring Satisfaction with Breasts (SB), Physical Wellbeing (PhW), Psychosocial Wellbeing (PsyW), and Sexual Wellbeing (SW) from 08/2020-02/2025. Additional questions assessed worry. Responses were compared to published normative controls using descriptive statistics and two-sample t-tests.
Results:
83 high-risk participants (average age 41 years ± 10) reported significantly higher SB score (p = 0.018) and significantly lower PhW score (p = 0.039). There were no statistically significant differences for PsyW and SW. Most participants reported screenings increased their sense of control over breast cancer risk-reduction.
Conclusions:
Differences observed in SB and PhW suggest that high-risk screening may positively influence body image but negatively impacts PhW. Further work is needed to elucidate factors leading to these differences.
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